KITLG (Human) ELISA Kit
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Specification
Product Description
KITLG (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human KITLG in plasma, serum, and cell culture supernatants.
Suitable Sample
Cell Culture Supernatant, Plasma, Serum
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.156 to 40 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — KITLG
Entrez GeneID
4254Gene Name
KITLG
Gene Alias
DKFZp686F2250, KL-1, Kitl, MGF, SCF, SF, SHEP7
Gene Description
KIT ligand
Omim ID
184745Gene Ontology
HyperlinkGene Summary
This gene encodes the ligand of the tyrosine-kinase receptor encoded by the KIT locus. This ligand is a pleiotropic factor that acts in utero in germ cell and neural cell development, and hematopoiesis, all believed to reflect a role in cell migration. In adults, it functions pleiotropically, while mostly noted for its continued requirement in hematopoiesis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
mast cell growth factor|steel factor|stem cell factor
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Interactome
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Pathway
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Disease
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Publication Reference
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Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop.
Levina V, Marrangoni A, Wang T, Parikh S, Su Y, Herberman R, Lokshin A, Gorelik E.
Cancer Research 2009 Dec; 70(1):338.
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The role of stem cell factor and granulocyte-colony stimulating factor in brain repair during chronic stroke.
Piao CS, Gonzalez-Toledo ME, Xue YQ, Duan WM, Terao S, Granger DN, Kelley RE, Zhao LR.
Journal of Cerebral Blood Flow and Metabolism 2009 Feb; 29(4):759.
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The expression of stem cell factor and c-kit receptor in human asthmatic airways.
Al-Muhsen SZ, Shablovsky G, Olivenstein R, Mazer B, Hamid Q.
Clinical and Experimental Allergy 2004 Jun; 34(6):911.
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Elimination of human lung cancer stem cells through targeting of the stem cell factor-c-kit autocrine signaling loop.
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