LYZ (Human) ELISA Kit
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The standard curve is for the purpose of illustration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
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Specification
Product Description
LYZ (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human LYZ.
Suitable Sample
Cell Culture Supernatant, CSF, Plasma, Saliva, Serum, Urine, Milk
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
0.078 to 5 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — LYZ
Entrez GeneID
4069Gene Name
LYZ
Gene Alias
LZM
Gene Description
lysozyme (renal amyloidosis)
Gene Ontology
HyperlinkGene Summary
This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the anti-microbial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. Missense mutations in LYZ have been identified in heritable renal amyloidosis. [provided by RefSeq
Other Designations
1,4-beta-N-acetylmuramidase C|lysozyme|lysozyme C
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Interactome
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Disease
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Publication Reference
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Salivary lysozyme and prevalent hypertension.
Qvarnstrom M, Janket S, Jones JA, Nuutinen P, Baird AE, Nunn ME, Van Dyke TE, Meurman JH.
Journal of Dental Research 2008 May; 87(5):480.
Application：Quant, Human, Saliva from consecutive cardiac patients.
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The extracellular chaperone clusterin potently inhibits human lysozyme amyloid formation by interacting with prefibrillar species.
Kumita JR, Poon S, Caddy GL, Hagan CL, Dumoulin M, Yerbury JJ, Stewart EM, Robinson CV, Wilson MR, Dobson CM.
Journal of Molecular Biology 2007 May; 369(1):157.
Application：Quant, Recombinant protein.
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Human lysozyme gene mutations cause hereditary systemic amyloidosis.
Pepys MB, Hawkins PN, Booth DR, Vigushin DM, Tennent GA, Soutar AK, Totty N, Nguyen O, Blake CC, Terry CJ, et al..
Nature 1993 Apr; 362(6420):553.
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Salivary lysozyme and prevalent hypertension.
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