F9 (Human) ELISA Kit
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Specification
Product Description
F9 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human F9.
Suitable Sample
Cell Culture Samples, CSF, Plasma, Serum
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
1.563 to 100 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — F9
Entrez GeneID
2158Gene Name
F9
Gene Alias
FIX, HEMB, MGC129641, MGC129642, PTC
Gene Description
coagulation factor IX
Omim ID
306900Gene Ontology
HyperlinkGene Summary
This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq
Other Designations
Christmas factor|OTTHUMP00000024154|coagulant factor IX|factor 9|factor IX|plasma thromboplastic component
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Interactome
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Pathway
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Disease
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Publication Reference
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Coagulation factors with improved properties for hemophilia gene therapy.
Pipe SW.
Seminars in Thrombosis and Hemostasis 2004 Apr; 30(2):227.
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Elevated clotting factor levels and venous thrombosis.
Bertina RM.
Pathophysiology of Haemostasis and Thrombosis 2013 Sep; 33(5-6):395.
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Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein.
Bogdanov VY, Balasubramanian V, Hathcock J, Vele O, Lieb M, Nemerson Y.
Nature Medicine 2003 Apr; 9(4):458.
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Coagulation factors with improved properties for hemophilia gene therapy.
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