CCL22 (Human) ELISA Kit
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Specification
Product Description
CCL22 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human CCL22.
Suitable Sample
Cell Culture Supernatant, Plasma (heparin, EDTA), Serum
Sample Volume
100 uL
Label
HRP-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
31.2 to 2000 pg/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles.
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Applications
Quantification
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Gene Info — CCL22
Entrez GeneID
6367Gene Name
CCL22
Gene Alias
A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1
Gene Description
chemokine (C-C motif) ligand 22
Omim ID
602957Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq
Other Designations
CC chemokine STCP-1|macrophage-derived chemokine|small inducible cytokine A22|small inducible cytokine subfamily A (Cys-Cys), member 22|stimulated T cell chemotactic protein 1
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Publication Reference
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Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4.
Imai T, Chantry D, Raport CJ, Wood CL, Nishimura M, Godiska R, Yoshie O, Gray PW.
The Journal of Biochemical Chemistry 1998 Jan; 273(3):1764.
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Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells.
Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW.
The Journal of Experimental Medicine 1997 May; 185(9):1595.
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Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4.
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