IYD 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-IYD full-length
Host
Human
Theoretical MW (kDa)
33.4
Interspecies Antigen Sequence
Mouse (85); Rat (84)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-IYD antibody (H00389434-B01) by Western Blots.
SDS-PAGE Gel
IYD transfected lysate.
Western Blot
Lane 1: IYD transfected lysate ( 33.4 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — IYD
Entrez GeneID
389434GeneBank Accession#
NM_203395Protein Accession#
NP_981932Gene Name
IYD
Gene Alias
C6orf71, DEHAL1, dJ422F24.1
Gene Description
iodotyrosine deiodinase
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
iodotyrosine dehalogenase 1
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