MCOLN2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human MCOLN2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MCOLN2
Entrez GeneID
255231GeneBank Accession#
NM_153259.2Protein Accession#
NP_694991.2Gene Name
MCOLN2
Gene Alias
FLJ36691, TRP-ML2, TRPML2
Gene Description
mucolipin 2
Omim ID
607399Gene Ontology
HyperlinkGene Summary
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM
Other Designations
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Interactome
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Disease
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