DAND5 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant DAND5.
Immunogen
DAND5 (NP_689867, 90 a.a. ~ 188 a.a) partial recombinant protein with GST tag.
Sequence
PLNPQEVIQGMCKAVPFVQVFSRPGCSAIRLRNHLCFGHCSSLYIPGSDPTPLVLCNSCMPARKRWAPVVLWCLTGSSASRRRVKISTMLIEGCHCSPK
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — DAND5
Entrez GeneID
199699GeneBank Accession#
NM_152654Protein Accession#
NP_689867Gene Name
DAND5
Gene Alias
CER2, CERL2, CKTSF1B3, COCO, CRL2, DANTE, GREM3, MGC126849, SP1
Gene Description
DAN domain family, member 5
Omim ID
609068Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. [provided by RefSeq
Other Designations
cerberus 2|cerberus-like 2|cysteine knot superfamily 1, BMP antagonist 3|dante
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