Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

DHX36

Gene Alias

DDX36, G4R1, KIAA1488, MLEL1, RHAU

Gene Description

DEAH (Asp-Glu-Ala-His) box polypeptide 36

Gene Ontology

Gene Summary

This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq

Other Designations

DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36|G4 resolvase-1|RNA helicase associated with AU-rich element