SGMS2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SGMS2 partial ORF ( NP_689834, 2 a.a. - 80 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DIIETAKLEEHLENQPSDPTNTYARPAEPVEEENKNGNGKPKSLSSGLRKGTKKYPDYIQIAMPTESRNKFPLEWWKTG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.43
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SGMS2
Entrez GeneID
166929GeneBank Accession#
NM_152621Protein Accession#
NP_689834Gene Name
SGMS2
Gene Alias
MGC26963, SMS2
Gene Description
sphingomyelin synthase 2
Omim ID
611574Gene Ontology
HyperlinkGene Summary
Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. The protein encoded by this gene is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. The encoded protein is required for cell growth. Three transcript variants encoding the same protein have been found for this gene. There is evidence for more variants, but the full-length nature of their transcripts has not been determined
Other Designations
OTTHUMP00000162627|OTTHUMP00000162628|SM synthase|phosphatidylcholine:ceramide cholinephosphotransferase 2
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Interactome
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Disease
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