SH2D1B rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SH2D1B peptide using ARM Technology.
Immunogen
A synthetic peptide of human SH2D1B is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SH2D1B peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SH2D1B
Entrez GeneID
117157GeneBank Accession#
SH2D1BGene Name
SH2D1B
Gene Alias
EAT2
Gene Description
SH2 domain containing 1B
Omim ID
608510Gene Ontology
HyperlinkGene Summary
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).[supplied by OMIM
Other Designations
OTTHUMP00000029531|SH2 domain-containing molecule EAT2
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Interactome
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Pathway
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