CNTROB purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of CNTROB expression in transfected 293T cell line (H00116840-T01) by CNTROB MaxPab polyclonal antibody.
Lane 1: CNTROB transfected lysate(99.33 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CNTROB protein.
Immunogen
CNTROB (AAH21134.1, 1 a.a. ~ 903 a.a) full-length human protein.
Sequence
MATSADSPSSPLGAEDLLSDSSEPPGLNQVSSEVTSQLYASLRLSRQAEATARAQLYLPSTSPPHEGLDGFAQELSRSLSVGLEKNLKKKDGSKHIFEMESVRGQLQTMLQTSRDTAYRDPLIPGAGSERREEDSFDSDSTATLLNTRPLQDLSPSSSAQALEELFPRYTSLRPGPPLNPPDFQGLRDALDSEHTRRKHCERHIQSLQTRVLELQQQLAVAVAADRKKDTMIEQLDKTLARVVEGWNRHEAERTEVLRGLQEEHQAAELTRSKQQETVTRLEQSLSEAMEALNREQESARLQQRERETLEEERQALTLRLEAEQQRCCVLQEERDAARAGQLSEHRELETLRAALEEERQTWAQQEHQLKEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEVRRLEGELDTARRERDALQLEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHRKQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQLEEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVWTMPPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLSLLLGPSFQSQHSFQPLEPKPDLTSSTAGAFSALGAFHPDHRAERPFPEEDPGPDGEGLLKQGLPPAQLEGLKNFLHQLLETVPQNNENPSVDLLPPKSGPLTVPSWEEAPQVPRIPPPVHKTKVPLAMASSLFRVPEPPSSHSQGSGPSSGSPERGGDGLTFPRQLMEVSQLLRLYQARGWGALPAEDLLLYLKRLEHSGTDGRGDNVPRRNTDSRLGEIPRKEIPSQAVPRRLATAPKTEKPPARKKSGHPAPSSMRSRGGVWR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (85)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CNTROB expression in transfected 293T cell line (H00116840-T01) by CNTROB MaxPab polyclonal antibody.
Lane 1: CNTROB transfected lysate(99.33 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CNTROB
Entrez GeneID
116840GeneBank Accession#
BC021134.1Protein Accession#
AAH21134.1Gene Name
CNTROB
Gene Alias
LIP8, PP1221
Gene Description
centrobin, centrosomal BRCA2 interacting protein
Omim ID
611425Gene Ontology
HyperlinkGene Summary
CNTROB is a centrosomal protein that interacts with BRCA2 (MIM 600185) and is required for centriole duplication and cytokinesis (Zou et al., 2005 [PubMed 16275750]).[supplied by OMIM
Other Designations
LYST-interacting protein LIP8|centrosomal BRCA2 interacting protein
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Interactome
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Publication Reference
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Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.
Sarah Carden, Elisa Vitiello, Ivan Rosa E Silva, James Holder, Valentina Quarantotti, Kamal Kishore, Valar Nila Roamio Franklin, Clive D'Santos, Takashi Ochi, Mark van Breugel, Fanni Gergely.
Developmental Cell 2023 Nov; 58(21):2393.
Application：IF, Human, Mouse, Mouse NE115 cells, Human 29T or iPSC cells.
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Centriolar satellites- and hMsd1/SSX2IP-dependent microtubule anchoring is critical for centriole assembly.
Hori A, Peddie CJ, Collinson LM, Toda T.
Molecular Biology of the Cell 2015 Jun; 26(11):2005.
Application：IF, Human, U2OS, HeLa cells.
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Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method.
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