TMEM123 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
TMEM123 transfected lysate.
Western Blot
Lane 1: TMEM123 transfected lysate ( 22.99 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TMEM123 full-length
Host
Human
Theoretical MW (kDa)
22.99
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TMEM123 antibody (H00114908-B01) by Western Blots.
SDS-PAGE Gel
TMEM123 transfected lysate.
Western Blot
Lane 1: TMEM123 transfected lysate ( 22.99 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TMEM123
Entrez GeneID
114908GeneBank Accession#
NM_052932.2Protein Accession#
-Gene Name
TMEM123
Gene Alias
KCT3, PORIMIN, PORMIN
Gene Description
transmembrane protein 123
Omim ID
606356Gene Ontology
HyperlinkGene Summary
This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death. [provided by RefSeq
Other Designations
keratinocytes associated transmembrane protein 3|pro oncosis receptor inducing membrane injury|pro-oncosis receptor inducing membrane injury|serine/threonine-rich receptor
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