WBSCR22 monoclonal antibody (M11), clone 2E12
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant WBSCR22.
Immunogen
WBSCR22 (NP_059998.2, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (79)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of WBSCR22 transfected lysate using anti-WBSCR22 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with WBSCR22 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged WBSCR22 is 0.1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to WBSCR22 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — WBSCR22
Entrez GeneID
114049GeneBank Accession#
NM_017528Protein Accession#
NP_059998.2Gene Name
WBSCR22
Gene Alias
HASJ4442, HUSSY-3, MGC19709, MGC2022, MGC5140, PP3381, WBMT
Gene Description
Williams Beuren syndrome chromosome region 22
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq
Other Designations
Williams Beuren syndrome chromosome region 22 protein|Williams-Beuren candidate region putative methyltransferase
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Interactome
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Pathway
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