MRLC2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MRLC2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MRLC2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MRLC2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MRLC2
Entrez GeneID
103910GeneBank Accession#
MRLC2Gene Name
MRLC2
Gene Alias
MLC-B
Gene Description
myosin regulatory light chain MRLC2
Omim ID
609211Gene Ontology
HyperlinkGene Summary
The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM
Other Designations
OTTHUMP00000165806|OTTHUMP00000165807|OTTHUMP00000165808|myosin regulatory light chain MRCL2
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Pathway
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