G6PC3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human G6PC3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human G6PC3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human G6PC3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — G6PC3
Entrez GeneID
92579GeneBank Accession#
G6PC3Gene Name
G6PC3
Gene Alias
UGRP
Gene Description
glucose 6 phosphatase, catalytic, 3
Omim ID
611045Gene Ontology
HyperlinkGene Summary
This gene encodes the catalytic subunit of glucose-6-phosphatase (G6Pase). G6Pase is located in the endoplasmic reticulum (ER) and catalyzes the hydrolysis of glucose-6-phosphate to glucose and phosphate in the last step of the gluconeogenic and glycogenolytic pathways. Mutations in this gene result in autosomal recessive severe congenital neutropenia. Multiple transcript variants have been found for this gene, only one of which is expected to express a protein
Other Designations
G6Pase-beta|glucose-6-phosphatase catalytic subunit 3|ubiquitously expressed G6Pase catalytic subunit-related protein
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Interactome
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