DISP1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human DISP1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DISP1
Entrez GeneID
84976GeneBank Accession#
BC007734.2Protein Accession#
AAH07734.1Gene Name
DISP1
Gene Alias
DISPA, DKFZp434I0428, FLJ43740, MGC104180, MGC13130, MGC16796
Gene Description
dispatched homolog 1 (Drosophila)
Omim ID
607502Gene Ontology
HyperlinkGene Summary
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq
Other Designations
OTTHUMP00000036011|dispatched A
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Interactome
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Disease
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