MXD3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human MXD3 full-length ORF ( NP_112590.1, 1 a.a. - 206 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFVAGQEHSYSHGGGAWL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.9
Interspecies Antigen Sequence
Mouse (83); Rat (81)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MXD3
Entrez GeneID
83463GeneBank Accession#
NM_031300.2Protein Accession#
NP_112590.1Gene Name
MXD3
Gene Alias
BHLHC13, FLJ35523, MAD3, MGC2383, MYX
Gene Description
MAX dimerization protein 3
Omim ID
609450Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq
Other Designations
Max-associated protein 3|Max-interacting transcriptional repressor MAD3
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