MMRN2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of MMRN2 expression in transfected 293T cell line (H00079812-T01) by MMRN2 MaxPab polyclonal antibody.
Lane 1: MMRN2 transfected lysate(104.39 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MMRN2 protein.
Immunogen
MMRN2 (AAH94744.1, 1 a.a. ~ 949 a.a) full-length human protein.
Sequence
MILSLLFSLGGPLGWGLLGAWAQASSTSLSDLQSSRTPGVWKAEAEDTGKDPVGRNWCPYPMSKLVTLLALCKTEKFLIHSQQPCPQGAPDCQKVKVMYRMAHKPVYQVKQKVLTSLAWRCCPGYTGPNCEHHDSMAIPEPADPGDSHQEPQDGPVSFKPGHLAAVINEVEVQQEQQEHLLGDLQNDVHRVADSLPGLWKALPGNLTAAVMEANQTGHEFPDRSLEQVLLPHVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKRLHKAQEAPGTNGSLVLATPGAGARPEPDSLQARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAVSLAVDAHKAEGERARAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAALFGEEVLEEMSEQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELAARVTALEQASEPPRPAEHLEPSHDAGREEAATTALAGLARELQSLSNDVKNVGRCCEAEAGAGAASLNASLDGLHNALFATQRSLEQHQRLFHSLFGNFQGLMEANVSLDLGKLQTMLSRKGKKQQKDLEAPRKRDKKEAEPLVDIRVTGPVPGALGAALWEAGSPVAFYASFSEGTAALQTVKFNTTYINIGSSYFPEHGYFRAPERGVYLFAVSVEFGPGPGTGQLVFGGHHRTPVCTTGQGSGSTATVFAMAELQKGERVWFELTQGSITKRSLSGTAFGGFLMFKT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (66)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MMRN2 expression in transfected 293T cell line (H00079812-T01) by MMRN2 MaxPab polyclonal antibody.
Lane 1: MMRN2 transfected lysate(104.39 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MMRN2
Entrez GeneID
79812GeneBank Accession#
BC094744.1Protein Accession#
AAH94744.1Gene Name
MMRN2
Gene Alias
EMILIN3, ENDOGLYX1, EndoGlyx-1, FLJ13465
Gene Description
multimerin 2
Omim ID
608925Gene Ontology
HyperlinkOther Designations
EMILIN-like protein EndoGlyx-1|OTTHUMP00000020015|elastin microfibril interfacer 3
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Interactome
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Publication Reference
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Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.
Khan KA, Naylor AJ, Khan A, Noy PJ, Mambretti M, Lodhia P, Athwal J, Korzystka A, Buckley CD, Willcox BE, Mohammed F, Bicknell R.
Oncogene 2017 Jul; [Epub].
Application：IF, IHC-P, Human, Human pancreatic cancer sections, HUVEC .
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Blocking CLEC14A-MMRN2 binding inhibits sprouting angiogenesis and tumour growth.
Noy PJ, Lodhia P, Khan K, Zhuang X, Ward DG, Verissimo AR, Bacon A, Bicknell R.
Oncogene 2015 Nov; 34(47):5821.
Application：WB-Tr, Human, HUVEC, HEK293T cells.
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Multimerin-2 is a ligand for group 14 family C-type lectins CLEC14A, CD93 and CD248 spanning the endothelial pericyte interface.
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