ALG12 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human ALG12 partial ORF ( NP_077010, 369 a.a. - 425 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
NYPGGVAMQRLHQLVPPQTDVLLHIDVAAAQTGVSRFLQVNSAWRYDKREDVQPGTG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.01
Interspecies Antigen Sequence
Mouse (78); Rat (78)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — ALG12
Entrez GeneID
79087GeneBank Accession#
NM_024105Protein Accession#
NP_077010Gene Name
ALG12
Gene Alias
ECM39, MGC111358, MGC3136, PP14673, hALG12
Gene Description
asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq
Other Designations
alpha-1,6-mannosyltransferase ALG12|asparagine-linked glycosylation 12 homolog (S. cerevisiae, alpha-1,6-mannosyltransferase)|asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase)|dolichyl-P-mannose:Man-7-GlcNAc-2-PP-dolichyl-a
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Interactome
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Pathway
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