NOD2 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (79)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of NOD2 transfected lysate using rabbit polyclonal anti-NOD2 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-NOD2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-NOD2 (300 ul)
2. Antibody pair for WB: rabbit polyclonal anti-NOD2 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — NOD2
Entrez GeneID
64127Gene Name
NOD2
Gene Alias
ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
Gene Description
nucleotide-binding oligomerization domain containing 2
Gene Ontology
HyperlinkGene Summary
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq
Other Designations
NLR family, CARD domain containing 2|NOD-like receptor C2|OTTHUMP00000164224|caspase recruitment domain family, member 15|caspase recruitment domain protein 15|inflammatory bowel disease protein 1|nucleotide-binding oligomerization domain 2|nucleotide-bin
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Interactome
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Disease
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