DNASE2B DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DNASE2B DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MPQLCTRASSSEIPGRLLTTLQSAQGQKFLHFAKSDSFLDDIFAAWMAQRLKTHLLTETWQRKRQELPSNCSLPYHVYNIKAIKLSRHSYFSSYQDHAKWCISQKGTKNRWTCIGDLNRSPHQAFRSGGFICTQNWQIYQAFQGLVLYYESCK
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DNASE2B
Entrez GeneID
58511GeneBank Accession#
NM_058248.1Protein Accession#
NP_490649.1Gene Name
DNASE2B
Gene Alias
DLAD
Gene Description
deoxyribonuclease II beta
Omim ID
608057Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH. Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
DNase II-like acid DNase|OTTHUMP00000011481|endonuclease DLAD|lysosomal DNase II
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Interactome
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Pathway
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