GBA2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GBA2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human GBA2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GBA2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GBA2
Entrez GeneID
57704GeneBank Accession#
GBA2Gene Name
GBA2
Gene Alias
AD035, DKFZp762K054, KIAA1605, MGC16895
Gene Description
glucosidase, beta (bile acid) 2
Omim ID
609471Gene Ontology
HyperlinkGene Summary
This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq
Other Designations
OTTHUMP00000022759|bile acid beta-glucosidase|non-lysosomal glucosylceramidase
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