SH3MD2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SH3MD2 partial ORF ( NP_065921, 790 a.a. - 888 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVLNESRPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SH3RF1
Entrez GeneID
57630GeneBank Accession#
NM_020870Protein Accession#
NP_065921Gene Name
SH3RF1
Gene Alias
FLJ21602, KIAA1494, POSH, RNF142, SH3MD2
Gene Description
SH3 domain containing ring finger 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. [provided by RefSeq
Other Designations
SH3 multiple domains 2|plenty of SH3 domains|plenty of SH3s|ring finger protein 142
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Interactome
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Disease
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