PLEKHG5 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PLEKHG5 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PLEKHG5 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PLEKHG5 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PLEKHG5
Entrez GeneID
57449GeneBank Accession#
PLEKHG5Gene Name
PLEKHG5
Gene Alias
DSMA4, GEF720, KIAA0720, RP4-650H14.3
Gene Description
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that activates the nuclear factor kappa B (NFKB1) signaling pathway. Multations in this gene have been found in a family with distal spinal muscular atrophy. [provided by RefSeq
Other Designations
NFkB activating protein|OTTHUMP00000001050|OTTHUMP00000001051|OTTHUMP00000001054|novel PH domain-containing protein|pleckstrin homology domain containing family G member 5
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Interactome
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Disease
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