Products

Western Blot (Cell lysate)

DAZ3 polyclonal antibody (A01), Lot # 061025JCS1 Western Blot analysis of DAZ3 expression in U-2 OS ( Cat # L022V1 ).

Western Blot (Recombinant protein)

ELISA

Entrez GeneID

57054

GeneBank Accession#

NM_020364

Protein Accession#

NP_065097

Gene Name

DAZ3

Gene Alias

MGC126441, pDP1679

Gene Description

deleted in azoospermia 3

Omim ID

400027

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. [provided by RefSeq

Other Designations

OTTHUMP00000042590