PCDHGB6 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PCDHGB6 full-length
Host
Human
Theoretical MW (kDa)
90.31
Interspecies Antigen Sequence
Mouse (80); Rat (81)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PCDHGB6 antibody (H00056100-B01) by Western Blots.
SDS-PAGE Gel
PCDHGB6 transfected lysate.
Western Blot
Lane 1: PCDHGB6 transfected lysate ( 90.31 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PCDHGB6
Entrez GeneID
56100GeneBank Accession#
NM_032100.1Protein Accession#
NP_115271.1Gene Name
PCDHGB6
Gene Alias
PCDH-GAMMA-B6
Gene Description
protocadherin gamma subfamily B, 6
Omim ID
606303Gene Ontology
HyperlinkGene Summary
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq
Other Designations
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