DOK5 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human DOK5 partial ORF ( NP_808874, 130 a.a. - 198 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LQSVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.33
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DOK5
Entrez GeneID
55816GeneBank Accession#
NM_177959Protein Accession#
NP_808874Gene Name
DOK5
Gene Alias
C20orf180, MGC16926
Gene Description
docking protein 5
Omim ID
608334Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP. [provided by RefSeq
Other Designations
OTTHUMP00000031322|downstream of tyrosine kinase 5
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Interactome
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Disease
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