OTUB1 DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human OTUB1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHIFPEGSEPKVYLLYRPGHYDILYK
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — OTUB1
Entrez GeneID
55611GeneBank Accession#
NM_017670.2Protein Accession#
NP_060140.2Gene Name
OTUB1
Gene Alias
FLJ20113, FLJ40710, HSPC263, MGC111158, MGC4584, OTB1, OTU1
Gene Description
OTU domain, ubiquitin aldehyde binding 1
Omim ID
608337Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTU-domain Ubal-binding 1|otubain 1|ubiquitin-specific protease otubain 1
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