STAB2 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant STAB2.
Immunogen
STAB2 (NP_060034, 367 a.a. ~ 465 a.a) partial recombinant protein with GST tag.
Sequence
ERLRELNTEPRGKWQGRLTSFISLLDKAYAWPLSKLGPFTVLLPTDKGLKGFNVNELLVDNKAAQYFVKLHIIAGQMNIEYMNNTDMFYTLTGKSGEIF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (77)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — STAB2
Entrez GeneID
55576GeneBank Accession#
NM_017564Protein Accession#
NP_060034Gene Name
STAB2
Gene Alias
DKFZp434E0321, FEEL-2, FELE-2, FELL, FELL-2, FEX2, HARE, STAB-2
Gene Description
stabilin 2
Omim ID
608561Gene Ontology
HyperlinkGene Summary
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq
Other Designations
CD44-like precursor FELL|FAS1 EGF-like and X-link domain containing adhesion molecule-2|fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-2|hepatic hyaluronan clearance receptor|hyaluronan receptor for endocytosis|hy
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Disease
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