SAGE1 monoclonal antibody (M02), clone 5C1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SAGE1.
Immunogen
SAGE1 (NP_061136, 357 a.a. ~ 455 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PLPSNALSTVLPGLAYLATADMPAMSTRDQHATIIHNLREEKKDNSQPTPDNVLSAVTPELINLAGAGIPPMSTRDQYATVNHHVHEARMENGQRKQDN
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SAGE1 monoclonal antibody (M02), clone 5C1. Western Blot analysis of SAGE1 expression in K-562.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SAGE1 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — SAGE1
Entrez GeneID
55511GeneBank Accession#
NM_018666Protein Accession#
NP_061136Gene Name
SAGE1
Gene Alias
SAGE
Gene Description
sarcoma antigen 1
Omim ID
300359Gene Ontology
HyperlinkGene Summary
This gene belongs to a class of genes that are activated in tumors. These genes are expressed in tumors of different histologic types but not in normal tissues, except for spermatogenic cells and, for some, placenta. The proteins encoded by these genes appear to be strictly tumor specific, and hence may be excellent sources of antigens for cancer immunotherapy. This gene is expressed in sarcomas. [provided by RefSeq
Other Designations
OTTHUMP00000024088|putative tumor antigen
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