RCBTB1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human RCBTB1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human RCBTB1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human RCBTB1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — RCBTB1
Entrez GeneID
55213GeneBank Accession#
RCBTB1Gene Name
RCBTB1
Gene Alias
CLLD7, CLLL7, GLP, MGC33184, RP11-185C18.1
Gene Description
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
Omim ID
607867Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq
Other Designations
GDP/GTP exchange factor (GEF)-like protein|OTTHUMP00000018413|chronic lymphocytic leukemia deletion region gene 7
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Interactome
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