PHIP (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human PHIP partial ORF ( NP_060404, 1599 a.a. - 1705 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
TLSKSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTNSGEIIHKKRGRKPKKLQYAKPEDLEQNNVHPIRDEVLPSSTCNFLSETNNVKEDL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.51
Interspecies Antigen Sequence
Mouse (83); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PHIP
Entrez GeneID
55023GeneBank Accession#
NM_017934Protein Accession#
NP_060404Gene Name
PHIP
Gene Alias
FLJ20705, FLJ45918, MGC90216, WDR11, ndrp
Gene Description
pleckstrin homology domain interacting protein
Gene Ontology
HyperlinkGene Summary
PHIP binds the pleckstrin homology (PH) domain of insulin receptor substrate-1 (IRS1; MIM 147545), modulates insulin signaling, and plays a role in pancreatic beta cell growth and survival (Farhang-Fallah et al., 2000 [PubMed 11018022]; Podcheko et al., 2007 [PubMed 17636024]).[supplied by OMIM
Other Designations
OTTHUMP00000016771
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