POLR3K rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human POLR3K peptide using ARM Technology.
Immunogen
A synthetic peptide of human POLR3K is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human POLR3K peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — POLR3K
Entrez GeneID
51728GeneBank Accession#
POLR3KGene Name
POLR3K
Gene Alias
C11, C11-RNP3, My010, RPC10, RPC11, hRPC11
Gene Description
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
Omim ID
606007Gene Ontology
HyperlinkGene Summary
This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. [provided by RefSeq
Other Designations
DNA directed RNA polymerase III polypeptide K|RNA polymerase III subunit (hRPC11)|RNA polymerase III subunit CII
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