MYO15A monoclonal antibody (M01), clone 7F2
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant MYO15A.
Immunogen
MYO15A (NP_057323.2, 3432 a.a. ~ 3530 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PCILAINHNGLNFLSTETHELMVKFPLKEIQSTRTQRPTANSSYPYVEIALGDVAAQRTLQLQLEQGLELCRVVAVHVENLLSAHEKRLTLPPSEITLL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MYO15A is 3 ng/ml as a capture antibody.ELISA
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Gene Info — MYO15A
Entrez GeneID
51168GeneBank Accession#
NM_016239Protein Accession#
NP_057323.2Gene Name
MYO15A
Gene Alias
DFNB3, DKFZp686N18198, FLJ17274, FLJ31311, MYO15
Gene Description
myosin XVA
Gene Ontology
HyperlinkGene Summary
This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq
Other Designations
myosin XV|unconventional myosin-15
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