TRNT1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TRNT1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TRNT1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TRNT1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TRNT1
Entrez GeneID
51095GeneBank Accession#
TRNT1Gene Name
TRNT1
Gene Alias
CCA1, CGI-47, MtCCA
Gene Description
tRNA nucleotidyl transferase, CCA-adding, 1
Gene Ontology
HyperlinkGene Summary
The CCA-adding enzyme TRNT1 (EC 2.7.7.25) is an essential enzyme that catalyzes the addition of the CCA terminus to the 3-prime end of tRNA precursors. This reaction is a fundamental prerequisite for mature tRNAs to become aminoacylated and to participate in protein biosynthesis (Lizano et al., 2007 [PubMed 17204286]).[supplied by OMIM
Other Designations
mitochondrial CCA-adding tRNA-nucleotidyltransferase
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Interactome
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