SMARCAL1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SMARCAL1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SMARCAL1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SMARCAL1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SMARCAL1
Entrez GeneID
50485GeneBank Accession#
SMARCAL1Gene Name
SMARCAL1
Gene Alias
HARP, HHARP
Gene Description
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq
Other Designations
HepA-related protein|OTTHUMP00000164057|SMARCA-like protein 1|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a-like 1
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Interactome
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Disease
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