KCNIP3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human KCNIP3 protein.
Immunogen
KCNIP3 (NP_038462.1, 1 a.a. ~ 256 a.a) full-length human protein.
Sequence
MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI
Host
Mouse
Reactivity
Human, Rat
Interspecies Antigen Sequence
Rat (92)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
CSEN MaxPab polyclonal antibody. Western Blot analysis of CSEN expression in rat brain.Western Blot (Transfected lysate)
Western Blot analysis of KCNIP3 expression in transfected 293T cell line (H00030818-T01) by KCNIP3 MaxPab polyclonal antibody.
Lane 1: CSEN transfected lysate(28.16 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — KCNIP3
Entrez GeneID
30818GeneBank Accession#
NM_013434.4Protein Accession#
NP_038462.1Gene Name
KCNIP3
Gene Alias
CSEN, DREAM, KCHIP3, MGC18289
Gene Description
Kv channel interacting protein 3, calsenilin
Omim ID
604662Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
Other Designations
A-type potassium channel modulatory protein 3|DRE-antagonist modulator|Kv channel interacting protein 3|calsenilin, presenilin-binding protein, EF hand transcription factor|potassium channel interacting protein 3
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Interactome
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Disease
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