TRIB2 (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of TRIB2 transfected lysate using mouse monoclonal anti-TRIB2 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-TRIB2.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TRIB2 transfected lysate using mouse monoclonal anti-TRIB2 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-TRIB2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-TRIB2 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-TRIB2 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TRIB2
Entrez GeneID
28951Gene Name
TRIB2
Gene Alias
C5FW, GS3955, TRB2
Gene Description
tribbles homolog 2 (Drosophila)
Omim ID
609462Gene Ontology
HyperlinkGene Summary
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Other Designations
tribbles homolog 2
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Interactome
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Disease
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