KCNMB4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human KCNMB4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human KCNMB4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human KCNMB4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — KCNMB4
Entrez GeneID
27345GeneBank Accession#
KCNMB4Gene Name
KCNMB4
Gene Alias
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Gene Description
potassium large conductance calcium-activated channel, subfamily M, beta member 4
Omim ID
605223Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq
Other Designations
calcium-activated potassium channel beta 4 subunit|large conductance calcium-dependent potassium ion channel beta 4 subunit
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