DNAJC2 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DNAJC2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKGSPGDSYQKLILQLIHLMKCYLIQ
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DNAJC2
Entrez GeneID
27000GeneBank Accession#
BC056682.1Protein Accession#
AAH56682.1Gene Name
DNAJC2
Gene Alias
MPHOSPH11, MPP11, ZRF1, ZUO1
Gene Description
DnaJ (Hsp40) homolog, subfamily C, member 2
Omim ID
605502Gene Ontology
HyperlinkGene Summary
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq
Other Designations
M-phase phosphoprotein 11|zuotin related factor 1
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