PABPC1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PABPC1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PABPC1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PABPC1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PABPC1
Entrez GeneID
26986GeneBank Accession#
PABPC1Gene Name
PABPC1
Gene Alias
PAB1, PABP, PABP1, PABPC2, PABPL1
Gene Description
poly(A) binding protein, cytoplasmic 1
Omim ID
604679Gene Ontology
HyperlinkGene Summary
The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM
Other Designations
poly(A) binding protein, cytoplasmic 2|poly(A)-binding protein, cytoplasmic 2
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Interactome
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