ARFGAP3 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human ARFGAP3 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — ARFGAP3
Entrez GeneID
26286GeneBank Accession#
NM_014570.3Protein Accession#
NP_055385.2Gene Name
ARFGAP3
Gene Alias
ARFGAP1, FLJ45618
Gene Description
ADP-ribosylation factor GTPase activating protein 3
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq
Other Designations
ADP-ribosylation factor GTPase activating protein 1|OTTHUMP00000028526
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Interactome
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Disease
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