SOSTDC1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SOSTDC1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MLPPAIHFYLLPLACILMKSCLAFKNDATEILYSHVVKPVPAHPSSNSTLNQARNGGRHFSNTGLDRNTRVQVGCRELRSTKYISDGQCTSISPLKELVCAGECLPLPVLPNWIGGGYGTKYWSRRSSQEWRCVNDKTRTQRIQLQCQDGSTRTYKITVVTACKCKRYTRQHNESSHNFESMSPAKPVQHHRERKRASKSSKHSMS
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — SOSTDC1
Entrez GeneID
25928GeneBank Accession#
NM_015464.2Protein Accession#
NP_056279.1Gene Name
SOSTDC1
Gene Alias
CDA019, DKFZp564D206, ECTODIN, USAG1
Gene Description
sclerostin domain containing 1
Omim ID
609675Gene Ontology
HyperlinkGene Summary
This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq
Other Designations
cystine-knot containing secreted protein|ectodermal BMP inhibitor|uterine sensitization-associated protein-1
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