MTHFD1L DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MTHFD1L DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAVLALTDSLADMKARLGRMVVASDKSGQPVTADDLGVTGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGADIGMEKFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEENIQLVADGCCNLQKQIQITQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSVGGKGSVDLARAVREAASKRSRFQFLYDVQVPIVDKIRTIAQAVYGAKDIELSPEAQAKIDRYTQQGFGNLPICMAKTHLSLSHQPDKKGVPRDFILPISDVRASIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDTETEQVKGLF
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MTHFD1L
Entrez GeneID
25902GeneBank Accession#
BC008629.1Protein Accession#
AAH08629.1Gene Name
MTHFD1L
Gene Alias
DKFZp586G1517, FLJ21145, FTHFSDC1, MTC1THFS, dJ292B18.2
Gene Description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Omim ID
611427Gene Ontology
HyperlinkGene Summary
One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).[supplied by OMIM
Other Designations
OTTHUMP00000017418|formyltetrahydrofolate synthetase domain containing 1|mitochondrial C1-tetrahydrofolate synthase|mitochondrial C1-tetrahydrofolate synthetase
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Interactome
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Pathway
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Disease
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