DFNB31 monoclonal antibody (M05), clone 2D12
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Immunofluorescence
Immunofluorescence of monoclonal antibody to DFNB31 on HeLa cell . [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (36.74 KDa) .
-
Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DFNB31.
Immunogen
DFNB31 (NP_056219, 808 a.a. ~ 907 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GLLEPTSTLVRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHREAARIIAEAFKTKDRDYIDFLVTEFNVML
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to DFNB31 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — DFNB31
Entrez GeneID
25861GeneBank Accession#
NM_015404Protein Accession#
NP_056219Gene Name
DFNB31
Gene Alias
CIP98, DKFZp434N014, KIAA1526, RP11-9M16.1, USH2D, WHRN, WI
Gene Description
deafness, autosomal recessive 31
Gene Ontology
HyperlinkGene Summary
In rat brain, Cip98 interacts with a calmodulin-dependent serine kinase, CASK (MIM 300172), and may be involved in the formation of scaffolding protein complexes that facilitate synaptic transmission in the central nervous system (CNS) (Yap et al., 2003 [PubMed 12641734]). Mutations in this gene, also known as WHRN, cause DFNB31 (MIM 607084).[supplied by OMIM
Other Designations
CASK-interacting protein CIP98|OTTHUMP00000021976|OTTHUMP00000021978|whirlin
-
Interactome
-
Disease
-
Publication Reference
-
A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs.
Wouter H van der Valk , Edward S A van Beelen , Matthew R Steinhart , Carl Nist-Lund , Daniel Osorio , John C M J de Groot , Liang Sun , Peter Paul G van Benthem , Karl R Koehler , Heiko Locher.
Cell Reports 2023 Jun; 42(6):112623.
Application：IF, Human, Human stereocilia.
-
A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com