LDOC1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human LDOC1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDEEEEDDY
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — LDOC1
Entrez GeneID
23641GeneBank Accession#
NM_012317.2Protein Accession#
NP_036449.1Gene Name
LDOC1
Gene Alias
BCUR1, Mar7, Mart7
Gene Description
leucine zipper, down-regulated in cancer 1
Omim ID
300402Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq
Other Designations
OTTHUMP00000024174|breast cancer, up-regulated 1
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