DMN monoclonal antibody (M03A), clone 4G5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DMN.
Immunogen
DMN (NP_663780.1, 1466 a.a. ~ 1565 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VSNVEAIRSRTQEAGALGVSDRGSWRDADSRNDQAVGVSFKASAGEGDQAHREQGKEQAMFDKKVQLQRMVDQRSVISDEKKVALLYLDNEEEENDGHWF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (60); Rat (61)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — SYNM
Entrez GeneID
23336GeneBank Accession#
NM_145728Protein Accession#
NP_663780.1Gene Name
SYNM
Gene Alias
DMN, KIAA0353, SYN
Gene Description
synemin, intermediate filament protein
Omim ID
606087Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
desmuslin|synemin alpha|synemin beta
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