ZNFN1A3 monoclonal antibody (M01), clone 3H5-G7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant ZNFN1A3.
Immunogen
ZNFN1A3 (AAH32707, 1 a.a. ~ 509 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MEDIQTNAELKSTQEQSVPAESAAVLNDYSLTKSHEMENVDSGEGPANEDEDIGDDSMKVKDEYSERDENVLKSEPMGNAEEPEIPYSYSREYNEYENIKLERHVVSFDSSRPTSGKMNCDVCGLSCISFNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHTGEKPFKCHLCNYACQRRDALTGHLRTHSVEKPYKCEFCGRSYKQRSSLEEHKERCRTFLQSTDPGDTASAEARHIKAEMGSERALVLDRLASNVAKRKSSMPQKFIGEKRHCFDVNYNSSYMYEKESELIQTRMMDQAINNAISYLGAEALRPLVQTPPAPTSEMVPVISSMYPIALTRAEMSNGAPQELEKKSIHLPEKSVPSERGLSPNNSGHDSTDTDSNHEERQNHIYQQNHMVLSRARNGMPLLKEVPRSYELLKPPPICPRDSVKVINKEGEVMDVYRCDHCRVLFLDYVMFTIHMGCHGFRDPFECNMCGYRSHDRYEFSSHIARGEHRALLK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Isotype
IgG2b kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (81.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to IKZF3 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — IKZF3
Entrez GeneID
22806GeneBank Accession#
BC032707Protein Accession#
AAH32707Gene Name
IKZF3
Gene Alias
AIO, AIOLOS, ZNFN1A3
Gene Description
IKAROS family zinc finger 3 (Aiolos)
Omim ID
606221Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. [provided by RefSeq
Other Designations
aiolos|zinc finger protein, subfamily 1A, 3 (Aiolos)
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Interactome
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Disease
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Publication Reference
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Ikaros family transcription factors in chronic and acute leukemia.
Matulic M, Paradzik M, Cicin-Sain L, Kapitanovic S, Dubravcic K, Batinic D, Antica M.
American Journal of Hematology 2009 Jun; 84(6):375.
Application:Flow Cyt, Human, Human peripheral blood cells.
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Ikaros family transcription factors in chronic and acute leukemia.
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