TMC6 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human TMC6 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — TMC6
Entrez GeneID
11322GeneBank Accession#
NM_007267.5Protein Accession#
NP_009198.3Gene Name
TMC6
Gene Alias
EV1, EVER1, EVIN1, FLJ17776, LAK-4P
Gene Description
transmembrane channel-like 6
Gene Ontology
HyperlinkGene Summary
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq
Other Designations
epidermodysplasia verruciformis 1|expressed in activated T/LAK lymphocytes
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Interactome
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Disease
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