FZD10 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human FZD10 peptide using ARM Technology.
Immunogen
A synthetic peptide of human FZD10 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human FZD10 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — FZD10
Entrez GeneID
11211GeneBank Accession#
FZD10Gene Name
FZD10
Gene Alias
CD350, FZ-10, FzE7, hFz10
Gene Description
frizzled homolog 10 (Drosophila)
Omim ID
606147Gene Ontology
HyperlinkGene Summary
This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq
Other Designations
frizzled 10
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Interactome
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Pathway
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Disease
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